Dr. Gupta’s research focuses on understanding infectious and non-infectious diseases, including malaria, arboviral diseases, and eye disorders. His work integrates advanced genomics, transcriptomics, and proteomics with machine learning approaches to identify novel biomarkers for early diagnosis, treatment, and disease management. His team is committed to developing innovative, cost-effective diagnostic methods and leveraging data-driven models to enhance public health strategies for disease control. His interdisciplinary approach aims to bridge fundamental research with translational outcomes for global health improvement.

• 41 Gupta M, Arya S, Agrawal P, Gupta H, Sikka R. Unravelling the molecular tapestry of pterygium: insights into genes for diagnostic and therapeutic innovations. Eye (Lond). 2024 Jun 21. IF-2.8
• 40 Gupta H, Sharma S, Gilyazova I, Satyamoorthy K. Molecular tools are crucial for malaria elimination. Mol Biol Rep. 2024 Apr 20;51(1):555. IF-2.6
• 39 Upadhayay P, Singh N, Pandey M, Gupta H, Sikka R. Unveiling the link between lifestyle risk factors and diabetic retinopathy. International Journal of Diabetes in Developing Countries, 2024, 1-6. IF-0.7
• 38 Gilyazova I, Ivanova E, Gupta H, Mustafin A, Ishemgulov R, Izmailov A, Gilyazova G, Pudova E, Pavlov V, Khusnutdinova E. miRNA Expression Patterns in Early- and Late-Stage Prostate Cancer Patients: High-Throughput Analysis. Biomedicines. 2023; 11(11):3073. https://doi.org/10.3390/biomedicines11113073. IF-4.7
• 37 Gupta A, Skjefte M, Muppidi P, Sikka R, Pandey M, Bharti PK, Gupta H. Unravelling the Influence of Host Genetic Factors on Malaria Susceptibility in Asian Populations. Acta Tropica. 2024, 249:107055. IF-2.7 
• 36 Sikka R, Raina P, Soni R, Gupta H, Bhanwer AJS. Genomic profile of diabetic retinopathy in a north indian cohort. Mol Biol Rep (2023). https://doi.org/10.1007/s11033-023-08772-z. IF-2.8
• 35 Gilyazova I, Asadullina D, Kagirova E, Sikka R, Mustafin A, Ivanova E, Bakhtiyarova K, Gilyazova G, Gupta S, Khusnutdinova E, Gupta H, Pavlov V. MiRNA-146a-A Key Player in Immunity and Diseases. Int J Mol Sci. 2023 Aug 14;24(16):12767. IF-5.6
• 34 Mukhi B, Gupta H, Punnath K, Anvikar AR, Srivastava B, Ghosh SK. Artemisinin-based combination therapy successfully treated two hyperparasitaemic Plasmodium falciparum cases. J Infect Dev Ctries. 2023 May 31;17(5):725-731. IF-1.9
• 33 Muppidi P, Wright E, Wassmer SC, Gupta H. Diagnosis of cerebral malaria: Tools to reduce Plasmodium falciparum associated mortality. Frontiers in Cellular and Infection Microbiology. 2023. 13, 95.
• 32 Gupta H, Nema S, Bharti PK. Time to stimulate Plasmodium vivax research in India: A way forward. Asian Pacific Journal of Tropical Medicine. 2023; 16 (1), 1-2. IF-3.1
• 31 Martiáñez-Vendrell X, Skjefte M, Sikka R, Gupta H. Factors Affecting the Performance of HRP2-Based Malaria Rapid Diagnostic Tests. Trop Med Infect Dis. 2022 Sept 25; 7(10): 265. IF-2.9
• 30 Mohanty S, Sahu PK, Pattnaik R, Majhi M, Maharana S, Bage J, Mohanty A, Mohanty A, Bendszus M, Patterson C, Gupta H, Dondorp AM, Pirpamer L, Hoffmann A, Wassmer SC. Evidence of Brain Alterations in Noncerebral Falciparum Malaria. Clin Infect Dis. 2022 Aug 24;75(1):11-18. IF-11.8
• 29 Sikka R, Bharti PK, Gupta H. microRNAs: An opportunity to overcome significant challenges in malaria detection and control. Curr Res Pharmacol Drug Discov. 2022;3:100115.
• 28 Gupta H*, Wassmer SC*. Harnessing the Potential of miRNAs in Malaria Diagnostic and Prevention. Front Cell Infect Microbiol. 2021;11:793954. *Corresponding authors IF-5.7
• 27 Sahu PK, Hoffmann A, Majhi M, Pattnaik R, Patterson C, Mahanta KC, Mohanty AK, Mohanty RR, Joshi S, Mohanty A, Bage J, Maharana S, Seitz A, Bendszus M, Sullivan SA, Turnbull IW, Dondorp AM, Gupta H, Pirpamer L, Mohanty S, Wassmer SC. Brain Magnetic Resonance Imaging Reveals Different Courses of Disease in Pediatric and Adult Cerebral Malaria. Clin Infect Dis. 2021 Oct 5;73(7):e2387-e2396. IF-11.8
• 26 Raina P, Sikka R, Gupta H, Matharoo K, Bali SK, Singh V, Bhanwer A. Association of eNOS and MCP-1 Genetic Variants with Type 2 Diabetes and Diabetic Nephropathy Susceptibility: A Case-Control and Meta-Analysis Study. Biochem Genet. 2021 Aug;59(4):966-996. IF-2.4
• 25 Gupta H*, Sahu PK, Pattnaik R, Mohanty A, Majhi M, Mohanty AK, Pirpamer L, Hoffmann A, Mohanty S, Wassmer SC*. Plasma levels of hsa-miR-3158-3p microRNA on admission correlate with MRI findings and predict outcome in cerebral malaria. Clin Transl Med. 2021 Jun;11(6):e396. *Corresponding authors IF-10.6
• 24 Gupta H*, Rubio M, Sitoe A, Varo R, Cisteró P, Madrid L, Cuamba I, Jimenez A, Martiáñez-Vendrell X, Barrios D, Pantano L, Brimacombe A, Bustamante M, Bassat Q, Mayor A. Plasma MicroRNA Profiling of Plasmodium falciparum Biomass and Association with Severity of Malaria Disease. Emerg Infect Dis. 2021 Feb;27(2):430-442. *Corresponding authors IF-11.8
• 23 Galatas B, Mayor A, Gupta H, Balanza N, Jang IK, Nhamussua L, Simone W, Cisteró P, Chidimatembue A, Munguambe H, Saúte F, Aide P, Bassat Q. Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique. Malar J. 2020 Dec 7;19(1):451. IF-3.0
• 22 Mukhi B, Gupta H*, Wassmer SC, Anvikar AR, Ghosh SK. Haplotype of RNASE 3 polymorphisms is associated with severe malaria in an Indian population. Mol Biol Rep. 2020 Nov;47(11):8841-8848. *Corresponding authors IF-2.8
• 21 Gupta H, Galatas B, Chidimatembue A, Huijben S, Cisteró P, Matambisso G, Nhamussua L, Simone W, Bassat Q, Ménard D, Ringwald P, Rabinovich NR, Alonso PL, Saúte F, Aide P, Mayor A. Effect of mass dihydroartemisinin-piperaquine administration in southern Mozambique on the carriage of molecular markers of antimalarial resistance. PLoS One. 2020;15(10):e0240174. IF-3.7
• 20 Huijben S, Macete E, Mombo-Ngoma G, Ramharter M, Kariuki S, Desai M, Shi YP, Mwangoka G, Massougbodji A, Cot M, Ndam NT, Uberegui E, Gupta H, Cisteró P, Aponte JJ, González R, Menéndez C, Mayor A. Counter-Selection of Antimalarial Resistance Polymorphisms by Intermittent Preventive Treatment in Pregnancy. J Infect Dis. 2020 Jan 2;221(2):293-303. IF-6.4
• 19 Anvikar AR, van Eijk AM, Shah A, Upadhyay KJ, Sullivan SA, Patel AJ, Joshi JM, Tyagi S, Singh R, Carlton JM, Gupta H*, Wassmer SC*. Clinical and epidemiological characterization of severe Plasmodium vivax malaria in Gujarat, India. Virulence. 2020 Jan 1;11(1):730-738. *Corresponding authors IF-5.2
• 18 Smith-Aguasca R, Gupta H, Uberegui E, Maquina M, Saute F, Paaijmans KP, Mayor A, Huijben S. Mosquitoes as a feasible sentinel group for anti-malarial resistance surveillance by Next Generation Sequencing of Plasmodium falciparum. Malar J. 2019 Oct 17;18(1):351. IF-3.0
• 17 Fonseca AM, González R, Bardají A, Jairoce C, Rupérez M, Jiménez A, Quintó L, Cisteró P, Vala A, Sacoor C, Gupta H, Hegewisch-Taylor J, Brew J, Ndam NT, Kariuki S, López M, Dobaño C, Chitnis CE, Ouma P, Ramharter M, Abdulla S, Aponte JJ, Massougbodji A, Briand V, Mombo-Ngoma G, Desai M, Cot M, Nhacolo A, Sevene E, Macete E, Menéndez C, Mayor A. VAR2CSA Serology to Detect Plasmodium falciparum Transmission Patterns in Pregnancy. Emerg Infect Dis. 2019 Oct;25(10):1851-1860. IF-11.8
• 16 Gupta H*, Galatas B, Matambisso G, Nhamussua L, Cisteró P, Bassat Q, Casellas A, Macete E, Aponte JJ, Sacoor C, Alonso P, Saúte F, Guinovart C, Aide P, Mayor A. Differential expression of var subgroups and PfSir2a genes in afebrile Plasmodium falciparum malaria: a matched case-control study. Malar J. 2019 Sep 23;18(1):326. *Corresponding authors IF-3.0
• 15 Marco-Hernández J, Camprubí D, Aylagas C, Gupta H, Castro P. Failure of intravenous artesunate treatment for Plasmodium falciparum malaria in a splenectomized traveller: A diagnostic challenge. Travel Med Infect Dis. 2019 Jul - Aug;30:142-143. IF-12.0
• 14 Rodríguez-Valero N, Camprubí D, García-Guijarro E, Llenas-García J, Alejo-Cancho I, Cisteró P, Mayor A, Muñoz J, Gupta H. Suspected quinine resistant P. falciparum severe malaria possibly acquired in Ivory Coast. Parasitol Int. 2018 Dec;67(6):684-687. IF-1.9
• 13 Gupta H, Macete E, Bulo H, Salvador C, Warsame M, Carvalho E, Ménard D, Ringwald P, Bassat Q, Enosse S, Mayor A. Drug-Resistant Polymorphisms and Copy Numbers in Plasmodium falciparum, Mozambique, 2015. Emerg Infect Dis. 2018 Jan;24(1):40-48. IF-11.8
• 12 Martínez-Pérez G, Lansana DP, Omeonga S, Gupta H, Breeze-Barry B, González R, Bardají A, Sarukhan A, Goteh JDK, Tody E, Cisteró P, Benda B, Kercula JD, Kibungu FD, Meyer García-Sípido A, Bassat Q, Tarr-Attia CK, Mayor A. Prevalence of Plasmodium falciparum infection among pregnant women at first antenatal visit in post-Ebola Monrovia, Liberia. Malar J. 2018 Oct 11;17(1):357. IF-3.0
• 11 Gupta H, Matambisso G, Galatas B, Cisteró P, Nhamussua L, Simone W, Cunningham J, Rabinovich NR, Alonso P, Saute F, Aide P, Mayor A. Molecular surveillance of pfhrp2 and pfhrp3 deletions in Plasmodium falciparum isolates from Mozambique. Malar J. 2017 Oct 16;16(1):416. IF-3.0
• 10 Galatas B, Nhamussua L, Candrinho B, Mabote L, Cisteró P, Gupta H, Rabinovich R, Menéndez C, Macete E, Saute F, Mayor A, Alonso P, Bassat Q, Aide P. In-Vivo Efficacy of Chloroquine to Clear Asymptomatic Infections in Mozambican Adults: A Randomized, Placebo-controlled Trial with Implications for Elimination Strategies. Sci Rep. 2017 May 2;7(1):1356. IF-4.6
• 9 Gupta H, Chaudhari S, Rai A, Bhat S, Sahu PK, Hande MH, D'Souza SC, Shashikiran U, Satyamoorthy K. Genetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum. PLoS One. 2017;12(4):e0175702. IF-3.7
• 8 Magallón-Tejada A, Machevo S, Cisteró P, Lavstsen T, Aide P, Rubio M, Jiménez A, Turner L, Valmaseda A, Gupta H, De Las Salas B, Mandomando I, Wang CW, Petersen JE, Muñoz J, Gascón J, Macete E, Alonso PL, Chitnis CE, Bassat Q, Mayor A. Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria. PLoS Pathog. 2016 Nov;12(11):e1006011. IF-6.7
• 7 Gupta H, Dhunputh P, Bhatt AN, Satyamoorthy K, Umakanth S. Cerebral malaria in a man with Plasmodium vivax mono-infection: a case report. Trop Doct. 2016 Oct;46(4):241-245. IF-0.6
• 6 Gupta H, Srivastava S, Chaudhari S, Vasudevan TG, Hande MH, D'souza SC, Umakanth S, Satyamoorthy K. New molecular detection methods of malaria parasites with multiple genes from genomes. Acta Trop. 2016 Aug;160:15-22. IF-2.7
• 5 Gupta H, Afsal MP, Shetty SM, Satyamoorthy K, Umakanth S. Plasmodium vivax infection causes acute respiratory distress syndrome: a case report. J Infect Dev Ctries. 2015 Aug 29;9(8):910-3. IF-1.9
• 4 Gupta H, Jain A, Saadi AV, Vasudevan TG, Hande MH, D'Souza SC, Ghosh SK, Umakanth S, Satyamoorthy K. Categorical complexities of Plasmodium falciparum malaria in individuals is associated with genetic variations in ADORA2A and GRK5 genes. Infect Genet Evol. 2015 Aug;34:188-99. IF-3.2
• 3 Fernandes RC, Hasan M, Gupta H, Geetha K, Rai PS, Hande MH, D'Souza SC, Adhikari P, Brand A, Satyamoorthy K. Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population. Mol Genet Genomics. 2015 Jun;290(3):1155-68. IF-3.1
• 2 Gupta H, Sakharwade SC, Angural A, Kotambail A, Bhat GK, Hande MH, D'Souza SC, Rao P, Kumari V, Saadi AV, Satyamoorthy K. Evidence for genetic linkage between a polymorphism in the GNAS gene and malaria in South Indian population. Acta Trop. 2013 Dec;128(3):571-7. IF-2.7
• 1 Saadi AV*, Gupta H*, Angural A, Dhanya SK, Mony S, Oberoi D, D'Souza SC, Sahoo RC, Hande MH, Gopinath PM, Satyamoorthy K. Single nucleotide polymorphisms of ADRB2 gene and their association with susceptibility for Plasmodium falciparum malaria and asthma in an Indian population. Infect Genet Evol. 2013 Dec;20:140-7. *equal contribution IF-3.2

Awards

Competitive Fellowships/All India Entrance Exam Cleared

International Thesis Supervision

Scientific Activities

Miscellaneous Courses